Nucleosides and Analogues
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | 100.0% | 307.20 | 500 MG
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of which DNA is made. This product can be used as a substrate of UMP/CMP kinase to form dCDP upon phosphorylation to dCTP and supports DNA biosynthesis.
- Endogenous metabolite
- Deoxynucleotide building block for DNA
- Substrate for UMP/CMP kinase
- Supports DNA biosynthesis
Medchemexpress LLC 2'-Deoxycytidine-5'-triphosphate-d14 dilithium | 2687960-70-7 | 95.0% | 493.11 | C9D14Li2N3O13P3 | 1 MG
Isotopically labeled deoxycytidine triphosphate-d14 supplied as the dilithium salt for use in DNA synthesis and analytical workflows. It serves as a deuterium-labeled nucleotide for enzymatic incorporation, tracer studies, and quantitative mass spectrometry.
- Isotope-labeled for use as an internal standard and tracer in analytical workflows.
- Suitable for enzymatic DNA synthesis, PCR, and cDNA synthesis.
- Supplied as the dilithium salt to support aqueous solubility and handling.
- High purity consistent with analytical and molecular biology applications.
- Available in small-scale quantities for method development and validation.
![eMolecules 109389-30-2 | 5'-O-DMT-2'-DEOXYURIDINE-3'-CE-PHOSPHORAMIDITE | AstaTech | MFCD00036354 | 730.799 | C39H47N4O8P | 98.000 | COc1ccc(cc1)C(OC[C@H]1O[C@H](C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)n1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccc(OC)cc1 | 0.25g | 268504772](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502486511.JPG-250.jpg)
eMolecules 109389-30-2 | 5'-O-DMT-2'-DEOXYURIDINE-3'-CE-PHOSPHORAMIDITE | AstaTech | MFCD00036354 | 730.799 | C39H47N4O8P | 98.000 | COc1ccc(cc1)C(OC[C@H]1O[C@H](C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)n1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccc(OC)cc1 | 0.25g | 268504772
5'-O-DMT-2'-DEOXYURIDINE-3'-CE-PHOSPHORAMIDITE | AstaTech | 109389-30-2 | MFCD00036354 | 730.799 | C39H47N4O8P | 98.000 | COc1ccc(cc1)C(OC[C@H]1O[C@H](C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)n1ccc(=O)[nH]c1=O)(c1ccccc1)c1ccc(OC)cc1 | 0.25g | 268504772
Apexbio Technology LLC 5-Ethynyl-2'-deoxyuridine (5-EdU), 1g CAS# 61135-33-9
5-Ethynyl-2'-deoxyuridine (5-EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation. 5-EdU can be used as a replacement for BrdU (5-Bromo-2'-deoxyuridine) to measure de novo DNA synthesis during the S-phase of the cell cycle through click chemistry. Click chemistry is a method of covalently coupling an azide with an alkyne. 5-EdU has an alkyne handle that can be detected using azide-containing fluorescent probes through a highly efficient click chemistry reaction. In contrast to the use of BrdU, the new method does not require sample fixation or DNA denaturation. 5-EdU-labelled cells may be isolated to determine the transcript of cells, from neural cancer or tissues that have undergone division in vitro and in vivo. Other sizes are also available. Please inqury us for quote.
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 100.0% | 10 MM 1 ML
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. Additionally, 2'-deoxyuridine reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Reduces microglial activation.
- Improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury.
- Promising for Alzheimer's disease (AD) research.
Sigma Aldrich Fine Chemicals Biosciences 2'-Deoxycytidine >=99% (HPLC) | 951-77-9 | MFCD00006547 | 250MG
2'-Deoxycytidine >=99% (HPLC) | Purity: >=99% (HPLC) | Mol Wt: 227.22 | 951-77-9 | MFCD00006547 | 250MG
Research Products International Corp 5-Bromo-2-Deoxyuridine 250 MG
Thymidine analog used for study of DNA synthesis. This analog selectively incorporates into cellular DNA during S-phase. Supplied as white powder.
Chem-Impex International, Inc. 2'-Deoxycytidine | 951-77-9 | MFCD00006547 | 25G
2'-Deoxycytidine, 951-77-9, MFCD00006547, 25G
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphate | 1032-65-1 | MFCD00006546 | 99.99% | 307.20 | 25MG
2'-Deoxycytidine-5'-monophosphate is an endogenous metabolite and a deoxynucleotide building block of which DNA is made. It can serve as a substrate for UMP/CMP kinase to form dCDP upon phosphorylation to dCTP, thereby supporting DNA biosynthesis.
- Endogenous metabolite
- Deoxynucleotide building block for DNA
- Supports DNA biosynthesis
- For research use only
- Available in various quantities
- High purity (99.99%)
Sigma Aldrich Fine Chemicals Biosciences 5-Bromo-2′-deoxyuridine | 59-14-3 | MFCD00006529 | 5 g
5-Bromo-2′-deoxyuridine | Purity: ≥99% | Mol Wt: 307.10 | 59-14-3 | MFCD00006529 | 5 g
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 500 MG
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has shown promise in Alzheimer's disease (AD) research by reducing microglial activation and improving oxidative stress damage through modulation of glycolytic metabolism on Aβ25-35-induced brain injury.
- Associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Precursor in the synthesis of edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
Medchemexpress LLC 2'-deoxycytidine-2'-13C | >98.0% | 228.21 g/mol | C8 13CH13N3O4 | 1 MG
13C-labeled 2'-deoxycytidine supplied as a research-grade stable isotope standard for analytical and tracer studies. Supplied in a small 1 mg pack with reported high purity, it is intended for use in metabolite tracing, mass spectrometry calibration, and other analytical applications.
- Stable isotope labeled (13C) standard for analytical methods.
- Suitable for metabolite tracing and mass spectrometry quantitation.
- High reported purity (>98.0%).
- Supplied in a small research pack suitable for analytical use.
- Provided as a solid, easy to store and handle in laboratory settings.
Medchemexpress LLC 2'-Deoxycytidine (Standard) | 951-77-9 | 100.0% | 100 MG
2'-Deoxycytidine (Standard) is an endogenous metabolite and reference standard. It has a molecular weight of 227.22 and a formula of C9H13N3O4. It appears as a white to off-white solid and is intended for research and analytical applications.
- Used as an analytical standard and reference standard for assays.
- Commonly utilized in qualitative, quantitative, and methodological research experiments.
- Applications include HPLC, GC, and MS.
- Also classified as an endogenous metabolite and natural product.
Medchemexpress LLC 2'-Deoxyuridine-1'-13C | 478510-85-9 | 1MG
2'-Deoxyuridine-1'-13C is a stable isotope-labeled compound with the molecular formula C813CH12N2O5 and a molecular weight of 229.19. It appears as a white to off-white solid with an isotopic enrichment of 99%. This product is intended for research use only and has not been fully validated for medical applications.
- White to off-white solid appearance
- Isotopic enrichment of 99%
- Molecular formula C813CH12N2O5
- Intended for research use only
- Store powder at -20°C for up to 3 years or at 4°C for up to 2 years
- Store in solvent at -80°C for 6 months or at -20°C for 1 month